// Add unique nullable index 
string indexName = "IX_UQ_UniqueColumn";
string tableName = "dbo.ExampleClasses";
string columnName = "UniqueColumn";

Sql(string.Format(@"
    CREATE UNIQUE NONCLUSTERED INDEX {0}
    ON {1}({2}) 
    WHERE {2} IS NOT NULL;",
    indexName, tableName, columnName));